ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
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EC 1.13.12.15 is Orphan !
Common name :3,4-dihydroxyphenylalanine oxidative deaminase

Systematic name :3,4-dihydroxy-L-phenylalanine:oxygen oxidoreductase (deaminating)

Other names :3,4-dihydroxy-L-phenylalanine: oxidative deaminase
Oxidative deaminase
DOPA oxidative deaminase
DOPAODA
Comments :This enzyme is one of the three enzymes involved in L-dopa (3,4-dihydroxyphenylalanine) catabolism in the non-oxygenic phototrophic bacterium Rubrivivax benzoatilyticus OU5 (and not Rhodobacter sphaeroides OU5 as had been thought (1)), the other two being EC 4.3.1.22 (dihydroxyphenylalanine reductive deaminase) and EC 2.6.1.49 (3,4-dihydroxyphenylalanine transaminase). In addition to DOPA, the enzyme can also use L-tyrosine, L-phenylalanine, L-tryptophan and glutamate as substrate, but more slowly. The enzyme is inhibited by NADH and 2-oxoglutarate. One of the three enzymes involved in L-dopa (3,4-dihydroxyphenylalanine) catabolism in the non-oxygenic phototrophic bacterium Rubrivivax benzoatilyticus OU5 (and not Rhodobacter sphaeroides OU5 as had been thought), the other two being EC 4.3.1.22 and EC 2.6.1.49. In addition to DOPA, the enzyme can also use L-tyrosine, L-phenylalanine, L-tryptophan and glutamate as substrate, but more slowly. Inhibited by NADH and 2-oxoglutarate.

Created :EC 1.13.12.15 created 2008

BRENDA organisms :Rhodobacter sphaeroides
Sus scrofa

Swiss-ProtNo protein sequences are associated with EC 1.13.12.15 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 1.13.12.15 in TrEMBL

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for EC 1.13.12.15.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

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