ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
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EC used by the NC-IUBMBSorted by :
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EC 1.13.99.3 is Orphan !
Common name :Tryptophan 2'-dioxygenase

Systematic name :L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)

Other names :TSO
TSO I
TSO II
Indole-3-alkane alpha-hydroxylase
Indolyl-3-alkan alpha-hydroxylase
Tryptophan side chain oxidase
Tryptophan side chain oxidase II
Tryptophan side chain oxidase type I
Tryptophan side-chain alpha,beta-oxidase
Tryptophan side-chain oxidase
Cofactors : Heme.

Comments :A hemoprotein. Acts on a number of indole-3-alkane derivatives, oxidizing the 3-side-chain in the 2'-position. Best substrates were L-tryptophan and 5-hydroxy-L-tryptophan. Acts on a number of indole-3-alkane derivatives, oxidizing the 3-side-chain in the 2'-position. Best substrates are L-tryptophan and 5-hydroxy-L-tryptophan.

Created :EC 1.13.99.3 created 1984

KEGG MAP : 00380 Tryptophan metabolism

BRENDA organisms :Homo sapiens
Pseudomonas fluorescens
Pseudomonas sp.

Swiss-ProtNo protein sequences are associated with EC 1.13.99.3 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 1.13.99.3 in TrEMBL

Click here to Report Sequence Evidence
for EC 1.13.99.3.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

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