ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
   year of creation
   organism
EC used by the NC-IUBMBSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
   year of creation

Search by   NC-IUBMB EC number
   Enzyme name
   Species



ORENZA   Home Page
   About Orenza

   Download
   Report Sequence Evidence


EC 1.2.1.74 is Orphan !
Common name :Abieta-7,13-dien-18-al dehydrogenase

Systematic name :Abieta-7,13-dien-18-al:NAD(+) oxidoreductase

Other names :SafD
Comments :Abietic acid is the principle component of conifer resin. This enzyme catalyzes the last step of the pathway of abietic acid biosynthesis in Abies grandis (grand fir). The activity has been demonstrated in cell-free stem extracts of A. grandis, was present in the cytoplasm, and required NAD(+) as cofactor (1). The enzyme is expressed constitutively at a high level, and is not inducible by wounding of the plant tissue (2). Abietic acid is the principle component of conifer resin. This enzyme catalyzes the last step of the pathway of abietic acid biosynthesis in Abies grandis (grand fir). The activity has been demonstrated in cell-free stem extracts of A.grandis, was present in the cytoplasm, and required NAD(+) as cofactor. The enzyme is expressed constitutively at a high level, and is not inducible by wounding of the plant tissue.

Created :EC 1.2.1.74 created 2009, modified 2012

KEGG MAP : 01100 Metabolic pathways
01110 Biosynthesis of secondary metabolites
00904 Diterpenoid biosynthesis

BRENDA organisms :Abies grandis

Swiss-ProtNo protein sequences are associated with EC 1.2.1.74 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 1.2.1.74 in TrEMBL

Click here to Report Sequence Evidence
for EC 1.2.1.74.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

 Contact us / © orenza 2012