ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
   year of creation
   organism
EC used by the NC-IUBMBSorted by :
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   classes of activity
   KEGG metabolism pathway
   year of creation

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EC 2.5.1.114 is Orphan !
Common name :tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase

Systematic name :S-adenosyl-L-methionine:tRNA(Phe) (4-demethylwyosine(37)-C(7))-((3S)-3-amino-3-carboxypropyl)transferase

Other names :TYW2
tRNA-yW synthesizing enzyme-2
TRM12 (gene name)
Taw2 (gene name)
Comments :The enzyme, which is found in all eukaryotes and in the majority of Euryarchaeota (but not in the Crenarchaeota), is involved in the hypermodification of the guanine nucleoside at position 37 of tRNA leading to formation of assorted wye bases. This modification is essential for translational reading-frame maintenance.The eukaryotic enzyme is involved in biosynthesis of the tricyclic base wybutosine, which is found only in tRNA(Phe).

Created :EC 2.5.1.114 created 2013

BRENDA organisms :null

Swiss-ProtNo protein sequences are associated with EC 2.5.1.114 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 2.5.1.114 in TrEMBL

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for EC 2.5.1.114.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

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