ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
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   organism
EC used by the NC-IUBMBSorted by :
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   classes of activity
   KEGG metabolism pathway
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EC 3.1.21.8 is Orphan !
Common name :T(4) deoxyribonuclease II

Systematic name :-

Other names :T(4) endonuclease II
DenA (gene name)
Cofactors : Magnesium.

Comments :Requires Mg(2+). This phage T(4) enzyme is involved in degradation of host DNA. The enzyme primarily catalyzes nicking of the bottom strand of double stranded DNA between the first and second base pair to the right of a top-strand CCGC motif. Double-stranded breaks are produced 5- to 10-fold less frequently (3). It does not cleave the T4 native DNA, which contains 5-hydroxymethylcytosine instead of cytosine. This phage T(4) enzyme is involved in degradation of host DNA. The enzyme primarily catalyzes nicking of the bottom strand of double stranded DNA between the first and second base pair to the right of a top-strand CCGC motif. Double-stranded breaks are produced 5- to 10-fold less frequently. It does not cleave the T4 native DNA, which contains 5-hydroxymethylcytosine instead of cytosine.

Created :EC 3.1.21.8 created 2014

BRENDA organisms :null

Swiss-ProtNo protein sequences are associated with EC 3.1.21.8 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 3.1.21.8 in TrEMBL

Click here to Report Sequence Evidence
for EC 3.1.21.8.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

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