ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
   year of creation
   organism
EC used by the NC-IUBMBSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
   year of creation

Search by   NC-IUBMB EC number
   Enzyme name
   Species



ORENZA   Home Page
   About Orenza

   Download
   Report Sequence Evidence


EC 3.2.2.6 is Orphan !
Common name :ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase

Systematic name :NAD(+) glycohydrolase (cyclic ADP-ribose-forming)

Other names :NAD(+) nucleosidase
CD38 (gene name)
BST1 (gene name)
Comments :This multiunctional enzyme catalyzes both the synthesis and hydrolysis of cyclic ADP-ribose, a calcium messenger that can mobilize intracellular Ca(2+) stores and activate Ca(2+) influx to regulate a wide range of physiological processes. In addition, the enzyme also catalyzes EC 2.4.99.20, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase. cf. EC 3.2.2.5, NAD(+) glycohydrolase. This multiunctional enzyme catalyzes both the synthesis and hydrolysis of cyclic ADP-ribose, a calcium messenger that can mobilize intracellular Ca(2+) stores and activate Ca(2+) influx to regulate a wide range of physiological processes. In addition, the enzyme also catalyzes EC 2.4.99.20. Cf. EC 3.2.2.5.

Created :EC 3.2.2.6 created 1961, modified 2004, modified 2014

KEGG MAP : 01100 Metabolic pathways
00760 Nicotinate and nicotinamide metabolism

BRENDA organisms :Homo sapiens
Neurospora crassa
Oryctolagus cuniculus
Ovis aries
Pseudomonas putida
Rattus norvegicus
Saccharomyces cerevisiae
Streptomyces griseus

Swiss-ProtNo protein sequences are associated with EC 3.2.2.6 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 3.2.2.6 in TrEMBL

Click here to Report Sequence Evidence
for EC 3.2.2.6.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

 Contact us / © orenza 2012