ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
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EC 4.2.3.141 is Orphan !
Common name :Sclareol synthase

Systematic name :(13E)-8-alpha-hydroxylabd-13-en-15-yl-diphosphate-lyase (sclareol forming)

Other names :SS
Cofactors : Manganese or magnesium.

Comments :Isolated from the plant Salvia sclarea (clary sage). Originally thought to be synthesized in one step from geranylgeranyl diphosphate it is now known to require two enzymes, EC 4.2.1.133, copal-8-ol diphosphate synthase and EC 4.2.3.141, sclareol synthase. Sclareol is used in perfumery. Isolated from the plant Salvia sclarea (clary sage). Originally thought to be synthesized in one step from geranylgeranyl diphosphate it is now known to require two enzymes, EC 4.2.1.133 and EC 4.2.3.141. Sclareol is used in perfumery. Formerly EC 3.1.7.4.

Created :EC 4.2.3.141 created 2013

KEGG MAP : 00904 Diterpenoid biosynthesis
01110 Biosynthesis of secondary metabolites

BRENDA organisms :null

Swiss-ProtNo protein sequences are associated with EC 4.2.3.141 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 4.2.3.141 in TrEMBL

Click here to Report Sequence Evidence
for EC 4.2.3.141.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

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