ORENZA : a database of ORphan ENZyme Activities

ORphan ENZyme ActivitiesSorted by :
   EC number
   classes of activity
   KEGG metabolism pathway
   year of creation
   organism
EC used by the NC-IUBMBSorted by :
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   KEGG metabolism pathway
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EC 6.3.2.35 is Orphan !
Common name :D-alanine--D-serine ligase

Systematic name :D-alanine:D-serine ligase (ADP-forming)

Other names :VanC
VanE
VanG
Comments :The product of this enzyme, D-alanyl-D-serine, can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide, which is formed by EC 6.3.2.4, D-alanine--D-alanine ligase. The resulting peptidoglycan does not bind the glycopeptide antibiotics vancomycin and teicoplanin, conferring resistance on the bacteria.

Created :EC 6.3.2.35 created 2010

BRENDA organisms :Enterococcus casseliflavus
Enterococcus faecalis
Enterococcus faecalis

Swiss-ProtNo protein sequences are associated with EC 6.3.2.35 in Swiss-Prot

TrEMBLNo protein sequences are associated with EC 6.3.2.35 in TrEMBL

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for EC 6.3.2.35.

Links to other databases
NC-IUBMB, INTENZ, ENZYME, PDB, BRENDA, KEGG, BIOCYC, PubMed,NCBI-Entrez

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